diff --git a/README.md b/README.md index c7cb22de5..cd4b5df10 100644 --- a/README.md +++ b/README.md @@ -29,11 +29,11 @@ Check out the [wiki page](https://github.com/smith-chem-wisc/MetaMorpheus/wiki) * Environment: * 64-bit operating system - * .NET Core 6.0: - * Windows: https://dotnet.microsoft.com/download/dotnet/thank-you/runtime-desktop-6.0.27-windows-x64-installer - * macOS, x64 Intel processor: https://dotnet.microsoft.com/download/dotnet/thank-you/runtime-6.0.27-macos-x64-installer - * macOS, ARM Apple Silicon processor: https://dotnet.microsoft.com/download/dotnet/thank-you/runtime-6.0.27-macos-arm64-installer - * Linux: https://docs.microsoft.com/dotnet/core/install/linux-package-managers + * .NET Core 8.0: + * Windows: https://dotnet.microsoft.com/en-us/download/dotnet/thank-you/sdk-8.0.401-windows-x64-installer + * macOS, x64 Intel processor: https://dotnet.microsoft.com/en-us/download/dotnet/thank-you/sdk-8.0.401-macos-x64-installer + * macOS, ARM Apple Silicon processor: https://dotnet.microsoft.com/en-us/download/dotnet/thank-you/sdk-8.0.401-macos-arm64-installer + * Linux: https://learn.microsoft.com/dotnet/core/install/linux?WT.mc_id=dotnet-35129-website * Note that the installer (MetaMorpheusInstaller.msi) only works on Windows. The command-line version of MetaMorpheus supports any operating system that supports .NET Core (Windows, MacOS, Linux) * 8 GB RAM recommended @@ -89,6 +89,8 @@ Long-read proteogenomic characterization: [Enhanced protein isoform characteriza Spectral library GPTMD search: [A Hybrid Spectral Library and Protein Sequence Database Search Strategy for Bottom-Up and Top-Down Proteomic Data Analysis, J of Proteome Res **2022**, _21_, 2609-2618](https://pubs.acs.org/doi/10.1021/acs.jproteome.2c00305) +Spectral Averaging: [Spectral averaging with outlier rejection algorithms to increase identifications in top-down proteomics](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11216233/) + ## mzLib, an all-purpose mass spectrometry toolchest implemented by MetaMorpheus [mzLib](https://github.com/smith-chem-wisc/mzLib) is a [nuget](https://www.nuget.org/packages/mzLib/) package that we created as an all-purpose toolchest for mass-spec data analysis and many of its functions provide the tools for MetaMorpheus. mzLib is freely available for use in mass-spec applications. You do not need to download mzLib separately to run MetaMorpheus; it is already included.