diff --git a/runtime/src/bank.rs b/runtime/src/bank.rs
index 4bbd825579d0e7..c96c1c42fc597f 100644
--- a/runtime/src/bank.rs
+++ b/runtime/src/bank.rs
@@ -3833,6 +3833,16 @@ impl Bank {
         // Bootstrap validator collects fees until `new_from_parent` is called.
         self.fee_rate_governor = genesis_config.fee_rate_governor.clone();
 
+        // Make sure to activate the account_hash_ignore_slot feature
+        // before calculating any account hashes.
+        if genesis_config
+            .accounts
+            .iter()
+            .any(|(pubkey, _)| pubkey == &feature_set::account_hash_ignore_slot::id())
+        {
+            self.activate_feature(&feature_set::account_hash_ignore_slot::id());
+        }
+
         for (pubkey, account) in genesis_config.accounts.iter() {
             assert!(
                 self.get_account(pubkey).is_none(),