diff --git a/integration/async-iterable-services-abort-signal/parameters.txt b/integration/async-iterable-services-abort-signal/parameters.txt
new file mode 100644
index 000000000..aab111ad9
--- /dev/null
+++ b/integration/async-iterable-services-abort-signal/parameters.txt
@@ -0,0 +1 @@
+useAsyncIterable=true,useAbortSignal=true
diff --git a/integration/async-iterable-services-abort-signal/simple.bin b/integration/async-iterable-services-abort-signal/simple.bin
new file mode 100644
index 000000000..51973c2d8
Binary files /dev/null and b/integration/async-iterable-services-abort-signal/simple.bin differ
diff --git a/integration/async-iterable-services-abort-signal/simple.proto b/integration/async-iterable-services-abort-signal/simple.proto
new file mode 100644
index 000000000..73d6a5180
--- /dev/null
+++ b/integration/async-iterable-services-abort-signal/simple.proto
@@ -0,0 +1,19 @@
+syntax = "proto3";
+package simple;
+
+// Echoer service returns the given message.
+service Echoer {
+  // Echo returns the given message.
+  rpc Echo(EchoMsg) returns (EchoMsg);
+  // EchoServerStream is an example of a server -> client one-way stream.
+  rpc EchoServerStream(EchoMsg) returns (stream EchoMsg);
+  // EchoClientStream is an example of client->server one-way stream.
+  rpc EchoClientStream(stream EchoMsg) returns (EchoMsg);
+  // EchoBidiStream is an example of a two-way stream.
+  rpc EchoBidiStream(stream EchoMsg) returns (stream EchoMsg);
+}
+
+// EchoMsg is the message body for Echo.
+message EchoMsg {
+  string body = 1;
+}
diff --git a/integration/async-iterable-services-abort-signal/simple.ts b/integration/async-iterable-services-abort-signal/simple.ts
new file mode 100644
index 000000000..c6ec3f2f8
--- /dev/null
+++ b/integration/async-iterable-services-abort-signal/simple.ts
@@ -0,0 +1,178 @@
+/* eslint-disable */
+import * as _m0 from "protobufjs/minimal";
+
+export const protobufPackage = "simple";
+
+/** EchoMsg is the message body for Echo. */
+export interface EchoMsg {
+  body: string;
+}
+
+function createBaseEchoMsg(): EchoMsg {
+  return { body: "" };
+}
+
+export const EchoMsg = {
+  encode(message: EchoMsg, writer: _m0.Writer = _m0.Writer.create()): _m0.Writer {
+    if (message.body !== "") {
+      writer.uint32(10).string(message.body);
+    }
+    return writer;
+  },
+
+  decode(input: _m0.Reader | Uint8Array, length?: number): EchoMsg {
+    const reader = input instanceof _m0.Reader ? input : new _m0.Reader(input);
+    let end = length === undefined ? reader.len : reader.pos + length;
+    const message = createBaseEchoMsg();
+    while (reader.pos < end) {
+      const tag = reader.uint32();
+      switch (tag >>> 3) {
+        case 1:
+          message.body = reader.string();
+          break;
+        default:
+          reader.skipType(tag & 7);
+          break;
+      }
+    }
+    return message;
+  },
+
+  // encodeTransform encodes a source of message objects.
+  // Transform<EchoMsg, Uint8Array>
+  async *encodeTransform(
+    source: AsyncIterable<EchoMsg | EchoMsg[]> | Iterable<EchoMsg | EchoMsg[]>,
+  ): AsyncIterable<Uint8Array> {
+    for await (const pkt of source) {
+      if (Array.isArray(pkt)) {
+        for (const p of pkt) {
+          yield* [EchoMsg.encode(p).finish()];
+        }
+      } else {
+        yield* [EchoMsg.encode(pkt).finish()];
+      }
+    }
+  },
+
+  // decodeTransform decodes a source of encoded messages.
+  // Transform<Uint8Array, EchoMsg>
+  async *decodeTransform(
+    source: AsyncIterable<Uint8Array | Uint8Array[]> | Iterable<Uint8Array | Uint8Array[]>,
+  ): AsyncIterable<EchoMsg> {
+    for await (const pkt of source) {
+      if (Array.isArray(pkt)) {
+        for (const p of pkt) {
+          yield* [EchoMsg.decode(p)];
+        }
+      } else {
+        yield* [EchoMsg.decode(pkt)];
+      }
+    }
+  },
+
+  fromJSON(object: any): EchoMsg {
+    return { body: isSet(object.body) ? String(object.body) : "" };
+  },
+
+  toJSON(message: EchoMsg): unknown {
+    const obj: any = {};
+    message.body !== undefined && (obj.body = message.body);
+    return obj;
+  },
+
+  fromPartial<I extends Exact<DeepPartial<EchoMsg>, I>>(object: I): EchoMsg {
+    const message = createBaseEchoMsg();
+    message.body = object.body ?? "";
+    return message;
+  },
+};
+
+/** Echoer service returns the given message. */
+export interface Echoer {
+  /** Echo returns the given message. */
+  Echo(request: EchoMsg, abortSignal?: AbortSignal): Promise<EchoMsg>;
+  /** EchoServerStream is an example of a server -> client one-way stream. */
+  EchoServerStream(request: EchoMsg, abortSignal?: AbortSignal): AsyncIterable<EchoMsg>;
+  /** EchoClientStream is an example of client->server one-way stream. */
+  EchoClientStream(request: AsyncIterable<EchoMsg>, abortSignal?: AbortSignal): Promise<EchoMsg>;
+  /** EchoBidiStream is an example of a two-way stream. */
+  EchoBidiStream(request: AsyncIterable<EchoMsg>, abortSignal?: AbortSignal): AsyncIterable<EchoMsg>;
+}
+
+export class EchoerClientImpl implements Echoer {
+  private readonly rpc: Rpc;
+  private readonly service: string;
+  constructor(rpc: Rpc, opts?: { service?: string }) {
+    this.service = opts?.service || "simple.Echoer";
+    this.rpc = rpc;
+    this.Echo = this.Echo.bind(this);
+    this.EchoServerStream = this.EchoServerStream.bind(this);
+    this.EchoClientStream = this.EchoClientStream.bind(this);
+    this.EchoBidiStream = this.EchoBidiStream.bind(this);
+  }
+  Echo(request: EchoMsg, abortSignal?: AbortSignal): Promise<EchoMsg> {
+    const data = EchoMsg.encode(request).finish();
+    const promise = this.rpc.request(this.service, "Echo", data, abortSignal || undefined);
+    return promise.then((data) => EchoMsg.decode(new _m0.Reader(data)));
+  }
+
+  EchoServerStream(request: EchoMsg, abortSignal?: AbortSignal): AsyncIterable<EchoMsg> {
+    const data = EchoMsg.encode(request).finish();
+    const result = this.rpc.serverStreamingRequest(this.service, "EchoServerStream", data, abortSignal || undefined);
+    return EchoMsg.decodeTransform(result);
+  }
+
+  EchoClientStream(request: AsyncIterable<EchoMsg>, abortSignal?: AbortSignal): Promise<EchoMsg> {
+    const data = EchoMsg.encodeTransform(request);
+    const promise = this.rpc.clientStreamingRequest(this.service, "EchoClientStream", data, abortSignal || undefined);
+    return promise.then((data) => EchoMsg.decode(new _m0.Reader(data)));
+  }
+
+  EchoBidiStream(request: AsyncIterable<EchoMsg>, abortSignal?: AbortSignal): AsyncIterable<EchoMsg> {
+    const data = EchoMsg.encodeTransform(request);
+    const result = this.rpc.bidirectionalStreamingRequest(
+      this.service,
+      "EchoBidiStream",
+      data,
+      abortSignal || undefined,
+    );
+    return EchoMsg.decodeTransform(result);
+  }
+}
+
+interface Rpc {
+  request(service: string, method: string, data: Uint8Array, abortSignal?: AbortSignal): Promise<Uint8Array>;
+  clientStreamingRequest(
+    service: string,
+    method: string,
+    data: AsyncIterable<Uint8Array>,
+    abortSignal?: AbortSignal,
+  ): Promise<Uint8Array>;
+  serverStreamingRequest(
+    service: string,
+    method: string,
+    data: Uint8Array,
+    abortSignal?: AbortSignal,
+  ): AsyncIterable<Uint8Array>;
+  bidirectionalStreamingRequest(
+    service: string,
+    method: string,
+    data: AsyncIterable<Uint8Array>,
+    abortSignal?: AbortSignal,
+  ): AsyncIterable<Uint8Array>;
+}
+
+type Builtin = Date | Function | Uint8Array | string | number | boolean | undefined;
+
+export type DeepPartial<T> = T extends Builtin ? T
+  : T extends Array<infer U> ? Array<DeepPartial<U>> : T extends ReadonlyArray<infer U> ? ReadonlyArray<DeepPartial<U>>
+  : T extends {} ? { [K in keyof T]?: DeepPartial<T[K]> }
+  : Partial<T>;
+
+type KeysOfUnion<T> = T extends T ? keyof T : never;
+export type Exact<P, I extends P> = P extends Builtin ? P
+  : P & { [K in keyof P]: Exact<P[K], I[K]> } & { [K in Exclude<keyof I, KeysOfUnion<P>>]: never };
+
+function isSet(value: any): boolean {
+  return value !== null && value !== undefined;
+}
diff --git a/src/generate-services.ts b/src/generate-services.ts
index ba8a4f311..2e7283424 100644
--- a/src/generate-services.ts
+++ b/src/generate-services.ts
@@ -62,6 +62,9 @@ export function generateService(
     const partialInput = options.outputClientImpl === "grpc-web";
     const inputType = requestType(ctx, methodDesc, partialInput);
     params.push(code`request: ${inputType}`);
+    if (options.useAbortSignal) {
+      params.push(code`abortSignal?: AbortSignal`);
+    }
 
     // Use metadata as last argument for interface only configuration
     if (options.outputClientImpl === "grpc-web") {
@@ -114,8 +117,13 @@ function generateRegularRpcMethod(
   const inputType = requestType(ctx, methodDesc);
   const rawOutputType = responseType(ctx, methodDesc, { keepValueType: true });
 
-  const params = [...(options.context ? [code`ctx: Context`] : []), code`request: ${inputType}`];
+  const params = [
+    ...(options.context ? [code`ctx: Context`] : []),
+    code`request: ${inputType}`,
+    ...(options.useAbortSignal ? [code`abortSignal?: AbortSignal`] : [])
+  ];
   const maybeCtx = options.context ? "ctx," : "";
+  const maybeAbortSignal = options.useAbortSignal ? "abortSignal || undefined," : "";
 
   let encode = code`${rawInputType}.encode(request).finish()`;
   let decode = code`data => ${rawOutputType}.decode(new ${Reader}(data))`;
@@ -163,7 +171,8 @@ function generateRegularRpcMethod(
         ${maybeCtx}
         this.service,
         "${methodDesc.name}",
-        data
+        data,
+        ${maybeAbortSignal}
       );
       return ${decode};
     }
@@ -329,6 +338,7 @@ export function generateRpcType(ctx: Context, hasStreamingMethods: boolean): Cod
   const { options } = ctx;
   const maybeContext = options.context ? "<Context>" : "";
   const maybeContextParam = options.context ? "ctx: Context," : "";
+  const maybeAbortSignalParam = options.useAbortSignal ? "abortSignal?: AbortSignal," : "";
   const methods = [[code`request`, code`Uint8Array`, code`Promise<Uint8Array>`]];
   if (hasStreamingMethods) {
     const observable = observableType(ctx);
@@ -348,7 +358,8 @@ export function generateRpcType(ctx: Context, hasStreamingMethods: boolean): Cod
         ${maybeContextParam}
         service: string,
         method: string,
-        data: ${method[1]}
+        data: ${method[1]},
+        ${maybeAbortSignalParam}
       ): ${method[2]};`);
   });
   chunks.push(code`    }`);
diff --git a/src/options.ts b/src/options.ts
index 20c48ef01..e84fa5059 100644
--- a/src/options.ts
+++ b/src/options.ts
@@ -65,6 +65,7 @@ export type Options = {
   outputSchema: boolean;
   onlyTypes: boolean;
   emitImportedFiles: boolean;
+  useAbortSignal: boolean;
   useExactTypes: boolean;
   useAsyncIterable: boolean;
   unknownFields: boolean;
@@ -112,6 +113,7 @@ export function defaultOptions(): Options {
     onlyTypes: false,
     emitImportedFiles: true,
     useExactTypes: true,
+    useAbortSignal: false,
     useAsyncIterable: false,
     unknownFields: false,
     usePrototypeForDefaults: false,
diff --git a/tests/options-test.ts b/tests/options-test.ts
index 6625b6c55..2bd64ecf1 100644
--- a/tests/options-test.ts
+++ b/tests/options-test.ts
@@ -40,6 +40,7 @@ describe("options", () => {
         "stringEnums": false,
         "unknownFields": false,
         "unrecognizedEnum": true,
+        "useAbortSignal": false,
         "useAsyncIterable": false,
         "useDate": "timestamp",
         "useExactTypes": true,