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crossgen_matrix_1item_TNiNc_20170130.m
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crossgen_matrix_1item_TNiNc_20170130.m
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%% Cross-generalization of T/Ni/Nc in 1-item displays. Done separately within each ROI
% using only T and Ni (so won't be confounded with object category)
% written by Tanya Wen
% 2017/01/30
dbstop if error
addpath('/imaging/tw05/Preparatory_Attention_Study/Version3-FullExp')
addpath('/imaging/local/software/spm_cbu_svn/releases/spm12_latest/')
addpath(genpath('/imaging/local/software/spm_toolbox/eeglab13_4_3b'))
spm('defaults', 'eeg');
% required software: libSVM & RSAtoolbox
workingdir = '/imaging/tw05/Preparatory_Attention_Study/Version3-FullExp';
addpath(genpath(fullfile(workingdir,'software','rsatoolbox')));
addpath(fullfile('/imaging/tw05/Preparatory_Attention_Study','software','libsvm-mat-2.87-1'));
% control variables
libSVMsettings='-s 1 -t 0'; % nu-SVM, linear
nRandomisations=1000;
rmpath('/hpc-software/matlab/r2015a/toolbox/bioinfo/biolearning/'); % to make sure libSVM code is used (not strictly necessary: matlab svmtrain yields exactly same model)
nfolds = 5;
% Define SUBJECT INFORMATION
subs = [1,2,3,4,5,6,7,8,9,10,11,13,15,16,17,18,19,20]; % subject numbers
subjects_dirs = {'meg16_0317/161107','meg16_0319/161110','meg16_0321/161111','meg16_0322/161114','meg16_0325/161115','meg16_0327/161117','meg16_0330/161121','meg16_0332/161122','meg16_0333/161124','meg16_0337/161128','meg16_0339/161129','meg16_0340/161129','meg16_0341/161201','meg16_0343/161202','meg16_0345/161206','meg16_0346/161206','meg16_0348/161208','meg16_0349/161208','meg16_0350/161212','meg16_0352/161213'};
subjnum = [1,2,3,4,5,6,1,2,3,4,5,6,1,2,3,4,5,6,6,2]; % counterbalancing numbers
%% parallelize
nw=96;
scheduler=cbu_scheduler();
scheduler.SubmitArguments='-q compute -l mem=200gb -l walltime=460800';
if isempty(gcp('nocreate')) || ~exist('pool','var') || pool.NumWorkers ~= nw,
if ~isempty(gcp('nocreate'))
delete(gcp('nocreate'))
end
scheduler.NumWorkers=nw;
pool=parpool(scheduler,nw);
end
for sub = subs
% go to subject directory
cd(workingdir)
swd = sprintf('sub%02d/%s',sub,subjects_dirs{sub}); % subject working directory
cd(swd)
%% load ROIs
roi_folder = '/imaging/tw05/Preparatory_Attention_Study/Version3-FullExp/ROIs';
% roi_list = {'MD_ESV.nii','MD_IPS.nii','MD_AI.nii','MD_postMFG.nii','MD_ACCpreSMA.nii',...
% 'MD_FEF.nii','MD_antMFG.nii','MD_midMFG.nii','Auditory_Te3.nii','Visual_hOc1.nii'};
roi_list = {'Auditory_Te3.nii','Visual_hOc1.nii','LPFC.nii'};
roinames=roi_list;
roinames = strrep(roinames, '_', '-');
roinames = strrep(roinames, '.nii', '');
for rois = 1:numel(roi_list)
Vroi = spm_vol(fullfile(roi_folder,roi_list{rois}));
[Y, XYZ]=spm_read_vols(Vroi);
coords = XYZ(:,Y>0)';
%% attentional template
% load data
D = spm_eeg_load('caefMattn2_attention_task_block1_raw.mat');
val = 1; %inversion method = MMN
% mark button press trials
bp_trials = []; % button press trials
devents = D.events;
for trial = 1:numel(D.events)
if ismember(4096,[devents{trial}.value]) == 1
bp_trials = [bp_trials trial];
end
end
D = badtrials(D, bp_trials, 1);
D.val=val;
D.inv{val}.source.XYZ = coords;
D.inv{val}.source.rad = 0;
D.inv{val}.source.label= {roinames{rois}};
D.inv{val}.source.fname = strcat(roinames{rois},'_attn2');
D.inv{val}.source.type = 'trials';
spm_eeg_inv_extract_tw(D);
Dattn = spm_eeg_load(strcat(roinames{rois},'_attn2'));
data3D = single(Dattn.fttimelock.trial);
% conds = Dattn.fttimelock.trialinfo;
conds = D.conditions;
%% define labels
% define subject specific pairings
allperms = perms([1 2 3]);
for i = 1:length(allperms)
if rem(subjnum(sub),6)+1 == i
choosetargets = allperms(i,:);
end
end
target1 = sprintf('image%d',choosetargets(1));
target2 = sprintf('image%d',choosetargets(2));
target3 = sprintf('image%d',choosetargets(3));
TNiNc = zeros(1,length(conds));
indexcue1 = strfind(conds,'cue1');
indexcue1 = ~cellfun(@isempty,indexcue1);
for findcue1 = 1:length(indexcue1)
if indexcue1(findcue1) == 1
for i = 1:3 %three events per trial
try % use try because if the last cue does not follow three trials it will crash
if strcmp(conds(findcue1+i),'cue1')==1 || strcmp(conds(findcue1+i),'cue2')==1
break
elseif strcmp(conds(findcue1+i),target1) == 1
TNiNc(findcue1+i) = 1; %target
elseif strcmp(conds(findcue1+i),target2) == 1
TNiNc(findcue1+i) = 2; %inconsistent non-target
elseif strcmp(conds(findcue1+i),target3) == 1
TNiNc(findcue1+i) = 3; %consistent non-target
elseif regexp(conds{findcue1+i},'imageall') == 1
TNiNc(findcue1+i) = -1; %three-item display (cue1)
else TNiNc(findcue1+i) = 0; %opaque
end
catch
end
end
end
end
indexcue2 = strfind(conds,'cue2');
indexcue2 = ~cellfun(@isempty,indexcue2);
for findcue2 = 1:length(indexcue2)
if indexcue2(findcue2) == 1
for i = 1:3 %three events per trial
try
if strcmp(conds(findcue2+i),'cue1')==1 || strcmp(conds(findcue2+i),'cue2')==1
break
elseif strcmp(conds(findcue2+i),target2) == 1
TNiNc(findcue2+i) = 1; %target
elseif strcmp(conds(findcue2+i),target1) == 1
TNiNc(findcue2+i) = 2; %inconsistent non-target
elseif strcmp(conds(findcue2+i),target3) == 1
TNiNc(findcue2+i) = 3; %consistent non-target
elseif regexp(conds{findcue2+i},'imageall') == 1
TNiNc(findcue2+i) = -2; %three-item display (cue2)
else TNiNc(findcue2+i) = 0; %opaque
end
catch
end
end
end
end
% need to remove T->Ni and Ni->T to overcome counterbalancing problem
% due to the lack of T->T and Ni->Ni trials
T_ind = find(TNiNc==1);
before_T_ind = T_ind-1;
before_T_Ni = intersect(before_T_ind,find(TNiNc==2)); % Ni->T
Ni_ind = find(TNiNc==2);
before_Ni_ind = Ni_ind-1;
before_Ni_T = intersect(before_Ni_ind,find(TNiNc==1)); % T->Ni
% D = badtrials(D, before_T_Ni, 1);
% D = badtrials(D, before_Ni_T, 1);
E = D;
E = badtrials(E, before_T_Ni+1, 1);
E = badtrials(E, before_Ni_T+1, 1);
% reformat to match Ds
clabel = {};
mark_rm_trials = [];
sortedTNiNc = [];
trialtypes = D.inv{1}.inverse.trials;
remove_ind = setdiff(E.indtrial(trialtypes,'BAD'), D.indtrial(trialtypes,'BAD'));
for i = 1:numel(trialtypes)
keep = D.indtrial(trialtypes{i}, 'GOOD');
remove_trialtypes{i} = remove_ind(ismember(D.conditions(remove_ind),trialtypes{i}));
rm_keep_ind = ismember(keep,remove_ind(ismember(D.conditions(remove_ind),trialtypes{i})));
mark_rm_trials = [mark_rm_trials rm_keep_ind];
clabel = [clabel D.conditions(keep)];
sortedTNiNc = [sortedTNiNc TNiNc(keep)];
end
sortedTNiNc(find(mark_rm_trials==1)) = 99;
% define targets, inconsistent non-targets
type = cell(1,2);
for i = 1:2
type{i} = find(sortedTNiNc==i);
end
%% smoothing option
smoothing = {'Raw','Smooth'};
for smooth = 1:numel(smoothing)
%% sliding time window
winsizes = 8;%[8,25,50,125]; %32ms,100ms,200ms,500ms
for winsize = winsizes
% set analysis time windows
twin_train = [1 size(data3D,3)]; % time of interest
stpsize = 1; %step size
trainwins = [twin_train(1):stpsize:(twin_train(2)-winsize)]';
trainwins(:,2) = trainwins(:,1) + winsize;
ntrains = size(trainwins,1);
twin_test = [1 size(data3D,3)]; % time of interest
testwins = [twin_test(1):stpsize:(twin_test(2)-winsize)]';
testwins(:,2) = testwins(:,1) + winsize;
ntests = size(testwins,1);
accuracy_matrix = nan(nfolds,ntrains,ntests);
predicted_vals = cell(nfolds,ntrains,ntests);
for fold = 1: nfolds
testind=[type{1}(fold:nfolds:end) type{2}(fold:nfolds:end)];
labels_test=sortedTNiNc(testind)';
trainind=setdiff([type{:}],testind);
labels_train=sortedTNiNc(trainind)';
parfor islide = 1:ntrains
itrain = data3D(:,:,trainwins(islide,1):trainwins(islide,2));
patternsTrain=double(itrain(trainind,:,:));
if smooth == 1 % no smoothing
patternsTrain=reshape(patternsTrain,length(trainind),[]);
elseif smooth == 2 % smoothing
patternsTrain = mean(patternsTrain,3);
end
% classification using linear SVM (train the classifier)
model=svmtrain(labels_train,patternsTrain,libSVMsettings);
for jslide = 1:ntests
itest = data3D(:,:,testwins(jslide,1):testwins(jslide,2));
patternsTest = double(itest(testind,:,:));
if smooth == 1 % no smoothing
patternsTest=reshape(patternsTest,length(testind),[]);
elseif smooth == 2 % smoothing
patternsTest = mean(patternsTest,3);
end
% classification using linear SVM (test the classifier)
[predicted,accuracy,~]=svmpredict(labels_test,patternsTest,model);
accuracy_matrix(fold,islide,jslide)=accuracy(1);
predicted_vals{fold,islide,jslide} = predicted;
end % nex slide
end % next slide
end % next fold
output_dir = 'crossgen_ROIs_1item_TNiNc';
try cd(output_dir)
catch eval(sprintf('!mkdir %s',output_dir)); cd(output_dir);
end
figure(sub)
imagesc(squeeze(mean(accuracy_matrix,1)));
colorbar;
caxis([1,100]);
% djm:
set(gca,'xticklabel',(cellfun(@str2double,get(gca,'xticklabel'))-1)*stpsize*4-100);
set(gca,'yticklabel',(cellfun(@str2double,get(gca,'yticklabel'))-1)*stpsize*4-100);
xlabel('start of test windows (ms)')
ylabel('start of train windows (ms)')
saveas(gcf,sprintf('CrossGenMatrix%03dms%s_%s_sub%s.png',winsize*4,smoothing{smooth},roinames{rois},num2str(sub)));
save(sprintf('CrossGenMatrix%03dms%s_%s_sub%s.mat',winsize*4,smoothing{smooth},roinames{rois},num2str(sub)));
close;
cd(workingdir)
cd(swd)
end % winsize
end % smooth
end % rois
end % sub
delete(gcp)