Research associated to CRISPR-Cas. Completed under Dr. Manuel Lladser at CU boulder
CRISPR-Cas9 Excision Therapy Suitability
BWA-based alignment of CRISPR gRNA spacer sequences
Fork of Azimuth (Machine Learning-Based Predictive Modelling of CRISPR/Cas9 guide efficiency), updated to work with Python 3.10+
Pre-trained models for the crisprScore package
Bowtie-based alignment of CRISPR gRNA spacer sequences
Search guide-RNA sequences given a genome or gene sequence
Useful human and mouse data for the crisprVerse ecosystem
Base functions and classes for CRISPR gRNA design
🔬 Genotyping tool for genome-edited samples, utilizing nanopore sequencer target sequencing
Tutorials for the crisprVerse
CRISPR/Cas-directed HDR genome editing suite: finds+scores gRNA targets, generates donor DNAs, & produces optimal cPCR primer designs.
Collection of R packages that work in harmony for CRISPR gRNA design
On-Target and Off-Target Scoring Algorithms for CRISPR gRNAs
Comprehensive design of CRISPR gRNAs for nucleases and base editors
Explore the cancer relevance of your gene list
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