diff --git a/altair/utils/core.py b/altair/utils/core.py
index 8ecaa896b..41e886001 100644
--- a/altair/utils/core.py
+++ b/altair/utils/core.py
@@ -397,6 +397,31 @@ def to_list_if_array(val):
     return df
 
 
+def sanitize_arrow_table(pa_table):
+    """Sanitize arrow table for JSON serialization"""
+    import pyarrow as pa
+    import pyarrow.compute as pc
+
+    arrays = []
+    schema = pa_table.schema
+    for name in schema.names:
+        array = pa_table[name]
+        dtype = schema.field(name).type
+        if str(dtype).startswith("timestamp"):
+            arrays.append(pc.strftime(array))
+        elif str(dtype).startswith("duration"):
+            raise ValueError(
+                'Field "{col_name}" has type "{dtype}" which is '
+                "not supported by Altair. Please convert to "
+                "either a timestamp or a numerical value."
+                "".format(col_name=name, dtype=dtype)
+            )
+        else:
+            arrays.append(array)
+
+    return pa.Table.from_arrays(arrays, names=schema.names)
+
+
 def parse_shorthand(
     shorthand,
     data=None,
diff --git a/altair/utils/data.py b/altair/utils/data.py
index 28e66bfab..c72fd2ea9 100644
--- a/altair/utils/data.py
+++ b/altair/utils/data.py
@@ -8,7 +8,7 @@
 from toolz import curried
 from typing import Callable
 
-from .core import sanitize_dataframe
+from .core import sanitize_dataframe, sanitize_arrow_table
 from .core import sanitize_geo_interface
 from .deprecation import AltairDeprecationWarning
 from .plugin_registry import PluginRegistry
@@ -166,7 +166,7 @@ def to_values(data):
     elif hasattr(data, "__dataframe__"):
         # experimental interchange dataframe support
         pi = import_pyarrow_interchange()
-        pa_table = pi.from_dataframe(data)
+        pa_table = sanitize_arrow_table(pi.from_dataframe(data))
         return {"values": pa_table.to_pylist()}
 
 
@@ -185,8 +185,6 @@ def check_data_type(data):
 # ==============================================================================
 # Private utilities
 # ==============================================================================
-
-
 def _compute_data_hash(data_str):
     return hashlib.md5(data_str.encode()).hexdigest()
 
diff --git a/pyproject.toml b/pyproject.toml
index 727690b22..d17777c24 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -70,7 +70,8 @@ dev = [
     "mypy",
     "pandas-stubs",
     "types-jsonschema",
-    "types-setuptools"
+    "types-setuptools",
+    "pyarrow>=11"
 ]
 doc = [
     "sphinx",
diff --git a/tests/utils/test_dataframe_interchange.py b/tests/utils/test_dataframe_interchange.py
new file mode 100644
index 000000000..6fc3a393f
--- /dev/null
+++ b/tests/utils/test_dataframe_interchange.py
@@ -0,0 +1,57 @@
+from datetime import datetime
+import pyarrow as pa
+import pandas as pd
+import pytest
+import sys
+import os
+
+from altair.utils.data import to_values
+
+
+def windows_has_tzdata():
+    """
+    From PyArrow: python/pyarrow/tests/util.py
+
+    This is the default location where tz.cpp will look for (until we make
+    this configurable at run-time)
+    """
+    tzdata_path = os.path.expandvars(r"%USERPROFILE%\Downloads\tzdata")
+    return os.path.exists(tzdata_path)
+
+
+# Skip test on Windows when the tz database is not configured.
+# See https://github.com/altair-viz/altair/issues/3050.
+@pytest.mark.skipif(
+    sys.platform == "win32" and not windows_has_tzdata(),
+    reason="Timezone database is not installed on Windows",
+)
+def test_arrow_timestamp_conversion():
+    """Test that arrow timestamp values are converted to ISO-8601 strings"""
+    data = {
+        "date": [datetime(2004, 8, 1), datetime(2004, 9, 1), None],
+        "value": [102, 129, 139],
+    }
+    pa_table = pa.table(data)
+
+    values = to_values(pa_table)
+    expected_values = {
+        "values": [
+            {"date": "2004-08-01T00:00:00.000000", "value": 102},
+            {"date": "2004-09-01T00:00:00.000000", "value": 129},
+            {"date": None, "value": 139},
+        ]
+    }
+    assert values == expected_values
+
+
+def test_duration_raises():
+    td = pd.timedelta_range(0, periods=3, freq="h")
+    df = pd.DataFrame(td).reset_index()
+    df.columns = ["id", "timedelta"]
+    pa_table = pa.table(df)
+    with pytest.raises(ValueError) as e:
+        to_values(pa_table)
+
+    # Check that exception mentions the duration[ns] type,
+    # which is what the pandas timedelta is converted into
+    assert "duration[ns]" in e.value.args[0]