diff --git a/packages/vite/src/node/optimizer/index.ts b/packages/vite/src/node/optimizer/index.ts
index 88e29418ca2a8a..0a2e793ecb1f27 100644
--- a/packages/vite/src/node/optimizer/index.ts
+++ b/packages/vite/src/node/optimizer/index.ts
@@ -299,6 +299,7 @@ function getDepHash(root: string, config: ResolvedConfig): string {
       alias: config.alias,
       dedupe: config.dedupe,
       assetsInclude: config.assetsInclude,
+      plugins: config.plugins.map((p) => p.name),
       optimizeDeps: {
         include: config.optimizeDeps?.include,
         exclude: config.optimizeDeps?.exclude