Releases: ACEnglish/kanpig
Releases · ACEnglish/kanpig
v0.3.1
Consistency improvements
- New filtering of haplotypes without paths increases accuracy
- New path scoring improves accuracy and consistency
- ZS and SS FORMAT fields replaced by KS reporting the score
- Requiring reads to span the full variant graph window including --chunksize buffer increases accuracy
- Exhaustive search of partial haplotypes
- Slight runtime reduction from avoidance of redundant path searches
Full Changelog: v0.3.0...v0.3.1
v0.3.0
General improvements
- ~8% speed increase from less work in the path-searching
- Partial haplotypes bug fix increases accuracy
- Fixed SQ and FT fields
- Dedicated writing thread helps reduce memory usage by preventing a backlog of completed variants while reading
- Default
--out
is stdout to allow easier compression/indexing (e.g.kanpig .. | bcftools sort -O z -o out.vcf.gz
) - IUPAC codes are fixed by kanpig according to vcf specifications (Issue #1)
- Fixed filtering of symbolic alts and BNDs
- Argument validation
Full Changelog: v0.2.0...v0.3.0
v0.2.0
- Up to 40% reduction in runtime
- Hemizygous and sex chromosome aware genotyping with new
--ploidy-bed
- Variants with alternate alleles of stars, monozygotic reference, and BNDs are filtered out
- Comparing PathScores by their average size and sequence similarity increases accuracy
Full Changelog: v0.1.2...v0.2.0
v0.1.2
- New optional hompolymer filter doesn't kmerize long homopolymers
- Improved logging info
- Correcting GQ field
- Correcting kmer counting
- Small speed/memory/io improvements
- Off-loaded annotation work from the single writer thread to the worker threads and using a large
multiple of page size for the BufWriter capacity - Fewer bam file opens
- Fewer clone operations
- Off-loaded annotation work from the single writer thread to the worker threads and using a large
Full Changelog: v0.1.0...v0.1.2