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@stjudeDNBBinfCore

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AntoniaChroni/README.md

Hi, I’m Tonia 😊

I’m a Senior Bioinformatics Research Scientist at the Bioinformatics Core at the St. Jude Children’s Research Hospital.

📊 🖇️ Support project analysis

🚀 🚧 👷 Build and automate computational workflows and pipelines

🧬 💪 Extensive experience with WGS/WES, sc-RNA-Seq, sc-ATAC-Seq and sc-TCR/BCR-Seq analysis in the context of tumor evolution and microenvironment

🐛 👷 Passionate about computation, automation and reproducibility for scientists

Research

I am an evolutionary computational biologist by training with extensive expertise in molecular evolution and phylogenetics, ecology and biogeography in the context of species and cancer.

📝 🚀 “Tumor Island Biogeography” (TIB) framework: I introduced TIB proposing that tumors are evolutionary islands and their heterogeneity can be explored by using omics data in the clinical setting (Chroni, 2024 and Chroni and Kumar, 2021).

📝 🚀 Co-developed PathFinder, a computational Bayesian method that uses the clone phylogeny, their genetic differentiation, and anatomical locations to infer cancer’s migration history in a patient.

😃 For more details on my work and research, please visit my digital 🏠 or my LinkedIn 🏠 or Google scholar profile.

Here’s some stats on my GitHub repos

My recent GitHub activity

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  1. stjudeDNBBinfCore/Trainings stjudeDNBBinfCore/Trainings Public

  2. stjudeDNBBinfCore/epigenomic-profiling-analysis stjudeDNBBinfCore/epigenomic-profiling-analysis Public

    HTML

  3. stjude-biohackathon/KIDS24-team1 stjude-biohackathon/KIDS24-team1 Public

    HTML 3

  4. kids-first/kf-dev-single-cell-rna kids-first/kf-dev-single-cell-rna Public

    Common Workflow Language 1

  5. d3b-center/pbta-ancestry d3b-center/pbta-ancestry Public

    HTML 1

  6. d3b-center/pbta-splicing d3b-center/pbta-splicing Public

    Splicing analysis across the PBTA

    HTML 1