SAID Study

Title: Normalized interferon signatures and clinical improvements by addition of IFNAR1 blockade in patients with type-I interferonopathy

Description

This repo is used for reproducing the figures and generating clinical reports for the patients included in the paper (add link here).

Contents

• data/ contains all the data needed for reproducing the figures and generating reports
• figures/ contains the example figures
• reports/ contains the example clinical reports
• func/ contains functions needed in the scripts
• reproduce figures.R used to reproduce figures
  • ISG-6 SAVI patient and the Mother in Figure 1B, 1C
  • ISG-34 SAVI patient and the Father in Figure 1E, 1F
  • ISG-1 CANDLE patient in Figure 2D
• clinical report generator.R used for generating the pdf reports with Rmarkdown
• normalized_counts.csv is the simplified data table of the reported patients and healthy controls

Contact

For any questions regarding data analyses, please contact petter.brodin@ki.se