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@GEMINI-multimorbidity

GEMINI

GEMINI: Genetic Evaluation of Multimorbidity towards INdividualisation of Interventions

GEMINI: Genetic Evaluation of Multimorbidity towards INdividualisation of Interventions.

We are studying links between 72 long-term conditions that could help improve interventions and treatments, using data from:

  • two large population-representative primary care datasets: CPRD and SIDIAP,
  • up to three sources of genetics data: UK Biobank, FinnGen, and multiple consortium meta-analyses (where available).

⭐ Our preprint is available! If you use these resources please cite the below and include the resource release version:

Murrin et al. (2024) A systematic analysis of the contribution of genetics to multimorbidity and comparisons with primary care data. medRxiv. https://doi.org/10.1101/2024.05.13.24307009

Resources available:

  • 📚 Harmonised diagnostic codes for each long-term condition ascertained in GEMINI.
  • 📦 R package {partialLDSC} to estimate partial genetic correlations from GWAS results.

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  1. GEMINI-LTC-code-list-Public GEMINI-LTC-code-list-Public Public

    Diagnostic codes for the long-term conditions (LTCs) used in the GEMINI project.

    1

  2. partialLDSC partialLDSC Public

    R package to estimate partial genetic correlations

    R 5

Repositories

Showing 5 of 5 repositories
  • Paper1-Supplementary-Tables Public

    A systematic analysis of the contribution of genetics to multimorbidity and comparisons with primary care data - Supplementary Tables

    GEMINI-multimorbidity/Paper1-Supplementary-Tables’s past year of commit activity
    0 0 0 0 Updated Oct 3, 2024
  • partialLDSC Public

    R package to estimate partial genetic correlations

    GEMINI-multimorbidity/partialLDSC’s past year of commit activity
    R 5 GPL-3.0 0 0 0 Updated Jul 26, 2024
  • gemini-multimorbidity.github.io Public

    GEMINI-multimorbidity organisation web pages

    GEMINI-multimorbidity/gemini-multimorbidity.github.io’s past year of commit activity
    JavaScript 0 0 0 0 Updated Jul 16, 2024
  • .github Public
    GEMINI-multimorbidity/.github’s past year of commit activity
    0 0 0 0 Updated Jul 16, 2024
  • GEMINI-LTC-code-list-Public Public

    Diagnostic codes for the long-term conditions (LTCs) used in the GEMINI project.

    GEMINI-multimorbidity/GEMINI-LTC-code-list-Public’s past year of commit activity
    1 0 0 0 Updated Jun 17, 2024

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