TCRdb contains more than 277 million highly reliable TCR sequences from over 8265 TCR-Seq samples across hundreds of tissues/clinical conditions/cell types. The unique features of TCRdb include:
- Comprehensive and reliable sequences for TCR repertoire in different samples generated by a strict and uniform pipeline of TCRdb;
- Powerful search function, allowing users to identify their interested TCR sequences in different conditions;
- Categorized sample metadata, enabling comparison of TCRs in different sample types;
- Interactive data visualization charts, describing the TCR repertoire in TCR diversity, length distribution and V-J gene utilization.
The TCRdb database is freely available at http://bioinfo.life.hust.edu.cn/TCRdb/
CATT .smk, MiXCR.smk, IMSEQ.smk: The parameters used for each method.
Download.smk： For data download from NCBI.
QC_single/double.smk: For raw data quanlity control.
All the pipepines were written in Snakemake.
Si-Yi Chen, Tao Yue, Qian Lei, An-Yuan Guo, TCRdb: a comprehensive database for T-cell receptor sequences with powerful search function, Nucleic Acids Research, , gkaa796, https://doi.org/10.1093/nar/gkaa796