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Update README
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phjanssen authored May 16, 2023
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## Figure scripts

- **01_dataset_description**: Strain and cell type composition of input datasets, as well as some additional statistics about the genotype estimation strategy (related to Figure 1, Suppl. Figure S2).
- **02_backgroundRNA_estimates**: Visualization of backround noise fractions per cell (related to Figure 2, Suppl. Figures S1,S3).
- **03_origin_of_background RNA**: Comparison of endogenous expression, background noise contamination and empty droplet profiles (related to Figure 3, Suppl. Figures S4,S5).
- **04_effect_on_downstream_analysis**: Impact of background noise on specificity and detectability of marker genes (related to Figure 4, Suppl. Figures S6,S7).
- **05_benchmark_estimation**: Comparison of background noise estimation accuracy of different computional methods (related to Figure 5, Suppl. Figure S8)
- **06_benchmark_downstream_analysis**: Summarizing the method comparison results on downstream analysis effect based on the Snakemake pipeline across datasets and parameter settings (related to Figure 6, Suppl. Figures S9-13).
- **01_dataset_description**: Strain and cell type composition of input datasets, as well as some additional statistics about the genotype estimation strategy (related to Figure 1, Suppl. Figure S3).
- **02_backgroundRNA_estimates**: Visualization of background noise fractions per cell (related to Figure 2, Suppl. Figures S1,S2,S4).
- **03_origin_of_background RNA**: Comparison of endogenous expression, background noise contamination and empty droplet profiles (related to Figure 3, Suppl. Figures S5,S6).
- **03_02_barcode_swapping**: Identification and quantification of barcode swapping events originating from PCR chimera (related to Suppl. Figure S7)
- **04_effect_on_downstream_analysis**: Impact of background noise on specificity and detectability of marker genes (related to Figure 4, Suppl. Figures S8,S9).
- **05_benchmark_estimation**: Comparison of background noise estimation accuracy of different computional methods (related to Figure 5, Suppl. Figure S10)
- **06_benchmark_downstream_analysis**: Summarizing the method comparison results on downstream analysis effect based on the Snakemake pipeline across datasets and parameter settings (related to Figure 6, Suppl. Figures S11-15).

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