Gene expression is encoded in all parts of a co-evolving interacting gene regulatory structure

Link to paper: 10.1038/s41467-020-19921-4

Figure. Illustration of four genes (CDC6, RIO2, NSP1, EXG1) that carry a group of motif co-occurrence rules with a common motif (NHP6B transcription factor binding site, blue line) in their promoter region. The genes diverge in possessing 2 to 4 other DNA motifs (red lines) across the remaining regulatory regions (promoter, 5' and 3' UTRs and terminator), which repurpose the expression of these genes across a range of almost 3 orders of magnitude of expression levels. Red lines in the histogram denote the specific expression levels of the genes.

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This repository contains scripts to reproduce the analysis and figures. The data is available at , extract the archive to a folder named 'data'.

Dependencies are provided in the conda environment.yml file in the 'docs' folder.