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scRNAseq-COPD

Welcome to the scRNAseq-COPD project! Chronic obstructive pulmonary disease (COPD) is a progressive disease that obstructs the airflow from the lungs, and tobacco smoking is the major cause of COPD. Here, we applied single-cell RNA sequencing to analyze COPD pathogenesis in COPD patients, non-COPD smokers and never-smokers and investigated the disease progression at single-cell resolution.

Samples in the dataset

COPD: JK02, JK05, JK07, JK08, JK09, JK10 Non-COPD smoker: JK01, JK03, JK04 Never Smoker: JK06, JK11, JK12

Links

Figshare https://figshare.com/articles/dataset/Single-cell_Transcriptome_Analysis_for_Chronic_Obstructive_Pulmonary_Disease/13340597

medRxiv https://www.medrxiv.org/content/10.1101/2020.12.03.20242412v1

This project has been published in American Journal of Respiratory Cell and Molecular Biology. https://pubmed.ncbi.nlm.nih.gov/36108172/

Contacts

Jun Nakayama, Ph.D. jnakayama.re@gmail.com

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