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bbrener1/README.md

Boris M Brenerman

Hi! I'm Boris! I've just defended a dissertation at Johns Hopkins about a new way of using random forest regressors to do single-cell biology. It's probably my best-written project right now, and you can check it out here:

https://github.com/bbrener1/rusty_axe

In the past I've done other kinds of biology work, like working on highly sensitive qPCR, good enough to detect not just a difference of a single base but good enough to detect non-standard DNA bases (lesions) in synthetic constructs. (https://www.nature.com/articles/s41598-017-12963-7, lol @ that url but it's really just Scientific Reports)

My main interest has been and will be the biology of aging, and I studied both molecular biology and bioinformatics to enable me to stage really cool experiments about the mechanisms of aging. Want to talk about detecting heteroplasmy at single-cell level to study the short-term evolutionary patterns of mt genomes? Want to rant about "damn it, why is stem cell depletion so all over the place? differentiation isn't that fancy a process, so how is the aging association backwards in every other tissue? It makes no sense!" at 3 am? Yeah, same, same.

Education:

  • Johns Hopkins University: PhD, Biology (2015-2021)
  • University of California, Santa Cruz: BS, Bioengineering (2009-2013)

Work

  • Johns Hopkins Medical School: Postdoc, Stein-O'Brien Lab (24-present)
  • Emerald Cloud Lab: Scientific Developer (2022-2023)
  • Johns Hopkins University: Research Assistant/Teaching Assistant (2015-2021)
  • National Institute on Aging: Postbaccalaureate Fellow (2013-2015)
  • University of California, Santa Cruz: Research Assistant (2010-2013)

Languages

Fluent:

  • Python
  • Rust
  • Russian

Can order lunch:

  • Bash

Biology

  • qPCR
  • Tissue culture
  • Primary line transfection
  • Protein cloning

Popular repositories Loading

  1. rusty_axe rusty_axe Public

    Jupyter Notebook 2

  2. johnston_retina johnston_retina Public

    Jupyter Notebook 1

  3. pythonihmm pythonihmm Public

    Python 1

  4. LADetector LADetector Public

    Forked from bxlab/LADetector

    LADetector package and scripts

    Perl

  5. gravity_clustering gravity_clustering Public

    Rust

  6. double_tree_cut double_tree_cut Public

    Rust 1