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SaberHQ authored Jun 17, 2019
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\* Notice: the use of `max_len` and `min_len` will affect the read length distributions. If the range between `max_len` and `min_len` is too small, the program will run slowlier accordingly.
\* Notice: the use of `max_len` and `min_len` in genome mode will affect the read length distributions. If the range between `max_len` and `min_len` is too small, the program will run slowlier accordingly.

__For example:__
__Example runs:__
1 If you want to simulate _E. coli_ genome, then circular command must be chosen because it's a circular genome
`./simulator.py genome -dna_type circular -rg Ecoli_ref.fasta -c ecoli`

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3 If you want to simulate _S. cerevisiae_ genome with kmer bias, then linear command must be chosen because it's a linear genome
`./simulator.py genome -dna_type linear -rg yeast_ref.fasta -c yeast --KmerBias`

_See more detailed example in example.sh_
4 If you want to simulate ten thousands cDNA/directRNA reads from mouse reference transcriptome
`./simulator.py transcriptome -rt Mus_musculus.GRCm38.cdna.all.fa -rg Mus_musculus.GRCm38.dna.primary_assembly.fa -c mouse_cdna -e abundance.tsv -n 10000`

4 If you want to simulate five thousands cDNA/directRNA reads from mouse reference transcriptome without modeling intron retention
`./simulator.py transcriptome -rt Mus_musculus.GRCm38.cdna.all.fa -c mouse_cdna -e abundance.tsv -n 5000 --no_model_ir`

## Explanation of output files
### 1. Characterization stage
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