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merge for hotfix release #125

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Oct 25, 2024
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2 changes: 2 additions & 0 deletions .gitignore
Original file line number Diff line number Diff line change
Expand Up @@ -6,3 +6,5 @@
setup.log
/tests/*.dSYM
/install
debug-scratch/
install_tmp/
5 changes: 5 additions & 0 deletions CHANGES.md
Original file line number Diff line number Diff line change
@@ -1,5 +1,10 @@
# CHANGES

## 1.15.5

* Fix memory bug in split
* Add debug option to setup.sh and Makefile

## 1.15.4

* Fix memory bug causing crash in generateCavemanUMNormVCF
Expand Down
17 changes: 14 additions & 3 deletions Makefile
Original file line number Diff line number Diff line change
@@ -1,9 +1,8 @@
CAVEMAN_VERSION=1.15.4
CAVEMAN_VERSION=1.15.5

TEST_REF?=""
#Compiler
CC?=gcc
CC+= -O3 -g -DCAVEMAN_VERSION='"$(CAVEMAN_VERSION)"' -DTEST_REF='"$(TEST_REF)"'
CC = gcc -DCAVEMAN_VERSION='"$(CAVEMAN_VERSION)"' -DTEST_REF='"$(TEST_REF)"'

#debug compiler
#CC = gcc -O3 -DCAVEMAN_VERSION='"$(CAVEMAN_VERSION)"' -g
Expand All @@ -13,6 +12,12 @@ CC+= -O3 -g -DCAVEMAN_VERSION='"$(CAVEMAN_VERSION)"' -DTEST_REF='"$(TEST_REF)"'
# -Wall turns on most warnings from compiler
CFLAGS = -Wall

ifneq ($(DEBUG),)
CFLAGS += -O3 # Optimise
else
CFLAGS += -g -O0 # Debug
endif

HTSLOC?=$(HTSLIB)

HTSTMP?=./caveman_tmp
Expand Down Expand Up @@ -73,8 +78,14 @@ all: clean make_bin make_htslib_tmp $(CAVEMAN_TARGET) $(UMNORM_TARGET) copyscrip
$(UMNORM_TARGET): $(OBJS)
$(CC) $(JOIN_INCLUDES) $(INCLUDES) $(CFLAGS) -o $(UMNORM_TARGET) $(OBJS) $(LFLAGS) $(CAT_LFLAGS) $(LIBS) ./src/generateCavemanVCFUnmatchedNormalPanel.c

ifneq ($(DEBUG),)
$(CAVEMAN_TARGET): $(OBJS)
$(CC) $(JOIN_INCLUDES) $(INCLUDES) $(CFLAGS) -o $(CAVEMAN_TARGET) $(OBJS) $(LFLAGS) $(CAT_LFLAGS) $(LIBS) ./src/caveman.c
else
$(CAVEMAN_TARGET): $(OBJS)
$(CC) $(JOIN_INCLUDES) $(INCLUDES) $(CFLAGS) -o $(CAVEMAN_TARGET) $(OBJS) $(LFLAGS) $(CAT_LFLAGS) $(LIBS) ./src/caveman.c
strip $(CAVEMAN_TARGET)
endif

#Unit Tests
test: $(CAVEMAN_TARGET)
Expand Down
59 changes: 39 additions & 20 deletions setup.sh
Original file line number Diff line number Diff line change
Expand Up @@ -32,12 +32,19 @@ function version_eq_gt() {

set -euo pipefail

if [ "$#" -ne "1" ] ; then
if [ "$#" -lt "1" ] ; then
echo "Please provide an installation path such as /opt/pancan"
exit 0
fi

INST_PATH=$1
DEBUG_ARG="${2:-}"
if [ "$DEBUG_ARG" = "DEBUG" ]; then
DEBUG_FLAG=1
echo "DEBUG set"
else
DEBUG_FLAG=0
fi

CPU=`grep -c ^processor /proc/cpuinfo`
if [ $? -eq 0 ]; then
Expand All @@ -52,9 +59,9 @@ echo "Max compilation CPUs set to $CPU"
# get current directory
INIT_DIR=`pwd`

set +o pipefail
LIBZ_VER=$(echo '#include <zlib.h>' | cpp -H -o /dev/null |& head -1 | cut -d' ' -f 2 | xargs grep -e '#define ZLIB_VERSION' | cut -d ' ' -f 3 | perl -pe 's/["\n]//g')
set -o pipefail
echo '#include <zlib.h>' | cpp -H 1>/dev/null 2> tmp.log.cpp
LIBZ_VER=$(cat tmp.log.cpp | head -1 | cut -d' ' -f 2 | xargs grep -e '#define ZLIB_VERSION' | cut -d ' ' -f 3 | sed 's/"//g')
rm tmp.log.cpp

if version_eq_gt $LIBZ_VER $REQUIRED_MIN_LIBZ ; then
echo "Found acceptable libz version $LIBZ_VER."
Expand Down Expand Up @@ -111,23 +118,35 @@ export HTSLIB="$SETUP_DIR/htslib"
export LD_LIBRARY_PATH="${LD_LIBRARY_PATH}:${HTSLIB}:${LINASM_LIB}"

echo -n "Building CaVEMan ..."
if [ -e "$SETUP_DIR/caveman.success" ]; then
echo -n " previously installed ...";
cd $INIT_DIR
make clean &&
{
if [ $DEBUG_FLAG -eq 1 ]; then
make -j$CPU DEBUG=1
else
cd $INIT_DIR
make clean &&
make -j$CPU &&
mv $INIT_DIR/bin/* $INST_PATH/bin/ &&
mkdir -p $INST_PATH/lib/ &&
cp $LINASM_LIB/liblinasm.so $INST_PATH/lib/. &&
touch $SETUP_DIR/caveman.success
make -j$CPU
fi
} &&
mv $INIT_DIR/bin/* $INST_PATH/bin/ &&
mkdir -p $INST_PATH/lib/ &&
cp $LINASM_LIB/liblinasm.so $INST_PATH/lib/. &&
touch $SETUP_DIR/caveman.success

# cleanup all junk
rm -rf $SETUP_DIR
make clean
# cleanup all intermediates
if [ -e "$SETUP_DIR/caveman.success" ]; then
echo
echo "Installation succesful"
echo "Binaries available at $INST_PATH/bin/"
echo "linasm.so available at $INST_PATH/lib/ - directory must be on LD_LIBRARY_PATH"
if [ $DEBUG_FLAG -eq 1 ]; then
echo "DEBUG set, retaining intermediate files"
else
rm -rf $SETUP_DIR
make clean
fi
else
echo
echo "Installation failed"
echo "Retaining intermediate files"
fi

echo
echo "Installation succesful"
echo "Binaries available at $INST_PATH/bin/"
echo "linasm.so available at $INST_PATH/lib/ - directory must be on LD_LIBRARY_PATH"
2 changes: 1 addition & 1 deletion src/alg_bean.h
Original file line number Diff line number Diff line change
Expand Up @@ -34,7 +34,7 @@
#define _alg_bean_h

#include <stdio.h>
#include <List.h>
#include "List.h"
#include "khash.h"

//New hash to store unique readlengths
Expand Down
12 changes: 6 additions & 6 deletions src/caveman.c
Original file line number Diff line number Diff line change
Expand Up @@ -30,12 +30,12 @@
*
*/

#include <setup.h>
#include <split.h>
#include <mstep.h>
#include <merge.h>
#include <estep.h>
#include <dbg.h>
#include "setup.h"
#include "split.h"
#include "mstep.h"
#include "merge.h"
#include "estep.h"
#include "dbg.h"
#include <stdio.h>
#include <stdlib.h>
#include <getopt.h>
Expand Down
2 changes: 1 addition & 1 deletion src/fai_access.c
Original file line number Diff line number Diff line change
Expand Up @@ -35,7 +35,7 @@
#include <string.h>
#include <stdlib.h>
#include "dbg.h"
#include <fai_access.h>
#include "fai_access.h"

int fai_access_get_name_from_index(int idx, char *index_file_name, char *chr_name, int *length){
assert(index_file_name != NULL);
Expand Down
6 changes: 3 additions & 3 deletions src/ignore_reg_access.c
Original file line number Diff line number Diff line change
Expand Up @@ -36,8 +36,8 @@
#include "dbg.h"
#include <string.h>
#include <limits.h>
#include <alg_bean.h>
#include <ignore_reg_access.h>
#include "alg_bean.h"
#include "ignore_reg_access.h"

int ignore_reg_access_get_ign_reg_count_for_chr(char *ign_file, char *chr){
assert(ign_file != NULL);
Expand Down Expand Up @@ -111,7 +111,7 @@ int ignore_reg_access_get_ign_reg_for_chr(char *ign_file,char *chr, int entry_co
int chk = sscanf(rd,"%s\t%d\t%d",chr_nom,&beg,&end);
if(chk==3){
if(strcmp(chr_nom,chr) == 0){
regions[found_count] = malloc(sizeof(struct seq_region_t));
regions[found_count] = malloc(sizeof(struct seq_region_t)); // not free'd :/
check_mem(regions[found_count]);
regions[found_count]->beg = beg + is_bed;
regions[found_count]->end = end;
Expand Down
2 changes: 1 addition & 1 deletion src/ignore_reg_access.h
Original file line number Diff line number Diff line change
Expand Up @@ -34,7 +34,7 @@
#define _ignore_reg_access_h

#include <stdio.h>
#include <List.h>
#include "List.h"

typedef struct seq_region_t{
int beg;
Expand Down
14 changes: 8 additions & 6 deletions src/split.c
Original file line number Diff line number Diff line change
Expand Up @@ -35,11 +35,11 @@
#include <getopt.h>
#include <string.h>
#include <assert.h>
#include <dbg.h>
#include <split.h>
#include <file_tests.h>
#include <alg_bean.h>
#include <fai_access.h>
#include "dbg.h"
#include "split.h"
#include "file_tests.h"
#include "alg_bean.h"
#include "fai_access.h"
#include <split_access.h>
#include <bam_access.h>
#include <config_file_access.h>
Expand Down Expand Up @@ -179,7 +179,7 @@ int split_main(int argc, char *argv[]){
int is_err = split_setup_options(argc,argv);
check(is_err==0,"Error parsing options");

char *chr_name = malloc(sizeof(char *));
char *chr_name = malloc(sizeof(char) * 100);
//Open the config file and do relevant things
FILE *config = fopen(config_file,"r");
check(config != NULL,"Failed to open config file for reading. Have you run caveman-setup?");
Expand Down Expand Up @@ -428,6 +428,8 @@ int split_main(int argc, char *argv[]){
hts_itr_destroy(iter_tum);
}//End of checking if this is a valid contig to split.

free(ignore_regs);
free(chr_name);

return 0;
error:
Expand Down
4 changes: 2 additions & 2 deletions src/split.h
Original file line number Diff line number Diff line change
Expand Up @@ -33,8 +33,8 @@
#ifndef _split_h
#define _split_h

#include <List.h>
#include <ignore_reg_access.h>
#include "List.h"
#include "ignore_reg_access.h"

int get_read_counts_with_ignore(List *ignore,int start, int stop, char *chr);
int shrink_section_to_size(char *chr_name,int sect_start, int sect_stop,
Expand Down