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DESCRIPTION
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Package: AllelicHeterogenitySimulator
Type: Package
Title: Computing and predicting gains in power owing to allelic heterogenity between population cohorts
Version: 0.1.0
Author: Christopher Neal Foley and Benjamin B Sun
Maintainer: Christopher Foley <chris.neal.foley@gmail.com> and Benjamin Sun <bbsun92@outlook.com>
Description: Simulation protocol to asssess impact of allelic enrichment on meta-analyses for 2 studies across a range of minor allele frequencies (in study 1) and allelic enrichment values (for study 2). Summary genetic association data are simulated, parameterised by observed association and disease prevelance data.
License: GPL-3
Encoding: UTF-8
LazyData: true
Depends: R (>= 3.5)
Imports:
plotly,
speedglm,
gridExtra,
grid,
ggplot2,
png,
tidyverse,
magrittr,
dplyr,
mrclust,
ggrepel
RoxygenNote: 7.1.1
Suggests:
knitr,
rmarkdown
VignetteBuilder: knitr