Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Annotation in develop branch produces different results #12

Closed
tjakobi opened this issue Jul 14, 2016 · 0 comments
Closed

Annotation in develop branch produces different results #12

tjakobi opened this issue Jul 14, 2016 · 0 comments
Assignees

Comments

@tjakobi
Copy link
Contributor

tjakobi commented Jul 14, 2016

While the positions of detected CircRNAs are the same between master and develop branch, the annotation itself differs.

Example:

631069 631291 RP5-857K21.6 0 + intron-exon exon,gene,transcript 1 631069 631369 RP5-857K21.6 0 + intron-exon exon,gene,transcript

1 631069 631291 RP5-857K21.6 0 + intron-exon transcript,gene,exon 1 631069 631369 RP5-857K21.6 0 + intron-exon transcript,gene,exon
Additionally to the cases with different annotation order in the type2 column, there are others cases:

1 10095461 10105744 UBE4B 2 + exon-exon CDS,exon,gene,transcript 1 10117459 10119613 UBE4B 2 + exon-exon CDS,exon,gene,transcript

vs.

1 10095461 10105744 UBE4B 2 + exon-intron gene,transcript 1 10117459 10119613 UBE4B 2 + exon-intron gene,transcript

And also cases where the type is different:

1 24514314 24514567 RCAN3 2 + exon-exon CDS,UTR,exon,gene,start_codon,transcript 1 24514314 24531391 RCAN3 2 + exon-exon CDS,UTR,exon,gene,start_codon,transcript

vs.

1 24514314 24514567 RCAN3 2 + exon-intron gene,transcript 1 24514314 24531391 RCAN3 2 + exon-intron gene,transcript

Type exon-exon vs. exon-intron.

@tjakobi tjakobi added the bug label Jul 14, 2016
@tjakobi tjakobi self-assigned this Jul 14, 2016
tjakobi added a commit that referenced this issue Jul 19, 2016
Annotation of circRNA regions has been corrected. Instead of only probing the interval (n,n) DCC now probes (n,n+1) and (n-1,n) for the left and right border respectively. This assures that the correct annotation is returned. For the special case the circRNA candidates start before and end after an annotated gene the candidate borders are now shown correctly as intergenic with the included linear gene annotation as hit.
@tjakobi tjakobi closed this as completed Jul 19, 2016
Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Projects
None yet
Development

No branches or pull requests

1 participant