To get you started 5 step procedure.
1. git clone https://github.com/floriankarsten/kirby3-mix-build-kit project
2. cd project
3. npm install
4. cd htdocs
5. composer install
Then point your webserver to htodcs/public folder.
In package.json there are scripts to run most notably for watching development npm run dev and for building to production npm run build.