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TitanCNA v1.15.0
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@gavinha gavinha released this 10 Aug 17:24
· 193 commits to master since this release
v1.15.0
74b27cf

TitanCNA version 1.15.0 changes

  1. 10X Genomics analysis
  • Please see scripts for instructions on running the 10X Genomics analysis.

  1. New script to help select optimal solutions. Please see scripts/R_scripts

  2. Added snakemake pipeline for entire TITAN workflow.
    Please see scripts/snakemake.

  3. New function

  • plotSegmentMedians()
  • loadHaplotypeAlleleCounts(): loads input allele counts with phasing information
  • plotHaplotypeFraction(): results from 10X Genomics WGS data with phasing of haplotype blocks
  1. Modified features (no changes for user-accessible functions)
  • updateParameters: coordinate descent estimate of ploidy update uses previously estimated normal parameter from the same corodinate descent iteration ; leads to faster convergence
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