To get set up:

# Install Python dependencies
pip install -r requirements.txt
# Copy the sample config file and edit it
cp config.sample.py config.py
vim config.py
# Create MySQL tables with config information from config.py
python manager.py db upgrade
# Start praw service for contacting reddit
praw-multiprocess
# Start a local server at http://localhost:5000
python manager.py runserver

To create a migration after a model change:

python manager.py db migrate -m ["migration comment"]