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Hitman

Install

On Windows, you should have Rtools.

Install Hitman from GitHub using remotes within R. You must install remotes, e.g. with install.packages("remotes"), if you haven't before. Hitman depends on ezlimma which depends on limma so you must also install these using instruction below if you haven't before.

#if haven't already installed limma
install.packages("BiocManager") #if haven't already installed BiocManager
library(BiocManager)
BiocManager::install("limma")

library(remotes)
remotes::install_github(repo="jdreyf/ezlimma", build_opts = c("--no-resave-data", "--no-manual"), build_vignettes = TRUE)
remotes::install_github(repo="jdreyf/Hitman", build_opts = c("--no-resave-data", "--no-manual"), build_vignettes = TRUE)

Usage

The vignette presents a tutorial. To see the vignette:

library(limma)
library(ezlimma)
library(Hitman)
library(rmarkdown)
browseVignettes(package="Hitman")

and click on HTML.

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High-throughput mediation analysis (Hitman)

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