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🧬 pq-genetics

When life gives you big challenges, just say "It's a peanut! 🥜" and watch them become as small as one!

A comprehensive toolkit for Population & Quantitative Genetics Analysis

Dedicated to the giants whose shoulders we stand on:
G.J. Mendel and D.S. Falconer

🔍 What's Inside?

Ready to Use 🚀

  • Inbreeding Coefficients
    • F_GRM (GRM-based inbreeding)
    • F_UNI (Uniting gametes correlation)
    • F_HOM (Homozygosity-based)
  • Principal Component Analysis (PCA)
  • Genome-Wide Association Studies (GWAS)
  • Genetic Data Management
    • Format conversions (PLINK/VCF)
    • Sample management
    • Data merging
    • Quality control
  • Genome Annotation
    • Feature annotation
    • Distribution visualization
    • GFF/GTF processing

Coming Soon 🌱

  • Effective Population Size (Ne)
  • Genetic Diversity Suite
    • H_O & H_E (Heterozygosity metrics)
    • Allelic Richness
    • F_ST & G_ST (Fixation indices)
  • Population Differentiation Tools
    • Pairwise F_ST
    • AMOVA analysis
  • Linkage Disequilibrium (LD)
    • LD decay curves
    • r² and D' calculations
  • Admixture Analysis
  • Selection Signatures
    • iHS scores
    • XP-EHH analysis
    • Tajima's D
  • Quantitative Genetics
    • Additive Genetic Variance
    • Breeding Values
    • Heritability estimates
    • Genetic Correlations
  • ROH Analysis
    • Homozygosity segments
    • ROH-based metrics

🚀 Getting Started

  1. Clone this treasure chest:
    git clone https://github.com/kkokay07/pq-genetics.git
  2. Navigate to your analysis of interest
  3. Follow the README.md - it's as easy as eating peanuts! 🥜

💡 Need Something Special?

Can't find what you're looking for? No worries - it's just a peanut! 🥜

Drop me a line at kkokay07@gmail.com and I'll help you crack it:

  • Custom metrics? Just ask!
  • Special analyses? I've got you!

🤝 Support Open Science

If you find this toolkit helpful and want to support open science and free education, consider contributing to:
UPI: 8618102886@ybl

👨‍🔬 About the Author

Dr. Kanaka K. K., PhD, ARS
Scientist
School of Bioinformatics
ICAR-Indian Institute of Agricultural Biotechnology, Ranchi

Be like IIAB!: IIAB is like yogic center where all the sciences (Plant, Animal, Aquatic,Mibrobiology, IT) meet to address emerging issues in food production.

🔎 Spy on me


Remember: Every analysis is just a peanut waiting to be cracked! 🥜

When the data seems overwhelming - just say "It's a peanut!"

When the statistics look scary - whisper "It's a peanut!"

When the code won't run - smile and say "It's a peanut!"


🥜 It's a peanut!

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