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Update cross-immunity parameters and appendix
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romain-ragonnet committed Sep 14, 2023
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6 changes: 3 additions & 3 deletions autumn/models/sm_covid2/params.yml
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Expand Up @@ -168,8 +168,8 @@ voc_emergence:
icu_risk_adjuster: 1.
cross_protection:
wild_type: 1.
delta: 0.68 # 32% immune escape DOI: 10.1503/cmaj.211248
omicron: .45 # 55% immune escape DOI: 10.1503/cmaj.211248
delta: 0.82 # https://doi.org/10.1016/S0140-6736(22)02465-5
omicron: 0.45 # https://doi.org/10.1016/S0140-6736(22)02465-5
delta:
starting_strain: false
seed_prop: 0.
Expand All @@ -185,7 +185,7 @@ voc_emergence:
cross_protection:
wild_type: 1.
delta: 1.
omicron: .45 # 55% immune escape DOI: 10.1503/cmaj.211248
omicron: .45 # https://doi.org/10.1016/S0140-6736(22)02465-5
omicron:
starting_strain: false
seed_prop: 0.
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Expand Up @@ -7,9 +7,9 @@

We assumed that individuals previously infected with the wild-type strain could only be reinfected with the delta or
omicron strains. However, such individuals have a reduced risk of infection with these variants compared to
infection-naive individuals (68\% and 45\% reduction for delta and omicron, respectively) \textcolor{red}{[REF DOI: 10.1503/cmaj.211248]}.
infection-naive individuals (82\% and 45\% reduction for delta and omicron, respectively) \cite{stein2023}.
We assumed that individuals previously infected with the delta variant could only be reinfected with the omicron variant,
with an infection risk reduced by 45\% compared to infection-naive individuals \textcolor{red}{[REF DOI: 10.1503/cmaj.211248]}.
with an infection risk reduced by 45\% compared to infection-naive individuals \cite{stein2023}.
The other parameters used to represent strain-specific characteristics are presented in Table \ref{param_table}.

Seeding of each new strain into the model was achieved through the importation of a small number (10 per million population) of new infectious persons with the relevant strain into the model.
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