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@neurogenomics

neurogenomics

Neurogenomics Lab, UK Dementia Research Institute at Imperial College London
README.md

🧠🧬 About Us 🧬🧠

Our research focuses on simple questions about complex brain traits: where do they occur (in which cell types)? When do they occur (at which developmental stages)? How do they occur (which quantitative traits of cells are affected)? We aim to develop the methods and datasets required to enable these questions to be answered systematically for any trait for which well-powered genetic data is available.

New to the lab? See here for our labwiki, or here for our YouTube channel


Visit our lab website to learn more! 🔗

Popular repositories Loading

  1. rworkflows rworkflows Public

    Continuous integration for R packages. 🔀 Automates testing ✅, documentation website building 📦, & containerised deployment 🐳.

    HTML 74 7

  2. MAGMA_Celltyping MAGMA_Celltyping Public

    Find causal cell-types underlying complex trait genetics

    R 70 31

  3. orthogene orthogene Public

    🧬 o r t h o g e n e 🧬✨✨✨✨✨✨✨ Interspecies gene mapping✨✨✨✨✨ 🦠 🔁 🌱 🔁 🌳 🔁 🍎 🔁 🍊 🔁 🪱 🔁 🪰 🔁 🐟 🔁 🦎 🔁 🐓 🔁 🦇 🔁 🐄 🔁 🐖 🔁 🐐 🔁 🐎 🔁 🐈 🔁 🐕 🔁 🐁 🔁 🐒 🔁 🦧 🔁 🦍 🔁 🏃‍♀️

    R 40 4

  4. reanalysis_Mathys_2019 reanalysis_Mathys_2019 Public

    A re-analysis of the [Single-cell transcriptomic analysis of Alzheimer’s disease](https://www.nature.com/articles/s41586-019-1195-2) using a standardised data processing and pseudobulk differential…

    HTML 14 4

  5. EpiCompare EpiCompare Public

    Comparison, benchmarking & QC of epigenetic datasets

    HTML 12 3

  6. scKirby scKirby Public

    Automated ingestion and conversion of various single-cell data formats, within and across species

    R 11 2

Repositories

Showing 10 of 84 repositories
  • MAGMA_Celltyping Public

    Find causal cell-types underlying complex trait genetics

    neurogenomics/MAGMA_Celltyping’s past year of commit activity
    R 70 31 11 0 Updated Oct 4, 2024
  • EnformerCelltyping Public

    Enformer Celltyping is a tensorflow, multi-headed attention based model that incorporates distal effects of Deoxyribonucleic Acid (DNA) interactions to predict histone marks across diverse cell types.

    neurogenomics/EnformerCelltyping’s past year of commit activity
    Jupyter Notebook 6 MIT 0 0 0 Updated Oct 4, 2024
  • rworkflows Public

    Continuous integration for R packages. 🔀 Automates testing ✅, documentation website building 📦, & containerised deployment 🐳.

    neurogenomics/rworkflows’s past year of commit activity
    HTML 74 7 31 (4 issues need help) 1 Updated Oct 2, 2024
  • scNLP Public

    Tools for applying natural language processing (NLP) techniques to single-cell (sc) omics data.

    neurogenomics/scNLP’s past year of commit activity
    Python 0 0 0 0 Updated Oct 2, 2024
  • PeakyFinders Public

    R package for mining, calling, and importing epigenomic peaks.

    neurogenomics/PeakyFinders’s past year of commit activity
    R 0 0 7 0 Updated Oct 2, 2024
  • phenomix Public

    Explore the phenome ✨🎆✨

    neurogenomics/phenomix’s past year of commit activity
    Jupyter Notebook 0 0 11 0 Updated Oct 2, 2024
  • scKirby Public

    Automated ingestion and conversion of various single-cell data formats, within and across species

    neurogenomics/scKirby’s past year of commit activity
    R 11 2 5 1 Updated Oct 2, 2024
  • EpiCompare Public

    Comparison, benchmarking & QC of epigenetic datasets

    neurogenomics/EpiCompare’s past year of commit activity
    HTML 12 3 13 0 Updated Oct 2, 2024
  • Power_Analysis_package Public

    Repo to wrap "scRNA-seq_Power_Analysis" work into an R package

    neurogenomics/Power_Analysis_package’s past year of commit activity
    R 0 0 0 0 Updated Sep 29, 2024
  • MSTExplorer Public

    Multi-Scale Target Explorer systematically identifies, prioritises, and visualises cell-type-specific gene therapy targets across the phenome.

    neurogenomics/MSTExplorer’s past year of commit activity
    R 1 1 3 0 Updated Sep 26, 2024
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