pk1cima: pk1cima: PK Sim of 1 Comp, IV Bolus

• pk1cima https://asan.shinyapps.io/pk1c
• pk1cima is open to everyone. We are happy to take your input. Please fork the repo, modify the codes and submit a pull request. https://github.com/asancpt/pk1c
• We are actively developing R pacakges, Shiny Apps, and Edison Science Apps regarding clinical pharmacology and pharmacometrics. Please check here. https://asancpt.github.io/softwares

Installation of NonCompart R Package

install.packages("NonCompart")
library(NonCompart)
tabNCA(Theoph, dose=320, concUnit="mg/L")

Help

• NonCompart package help https://cran.r-project.org/web/packages/NonCompart/NonCompart.pdf
• ncar package help https://cran.r-project.org/web/packages/ncar/ncar.pdf

References

Gabrielsson J, Weiner D. Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications. 5th ed. 2016.

Shargel L, Yu A. Applied Biopharmaceutics and Pharmacokinetics. 7th ed. 2015.

Rowland M, Tozer TN. Clinical Pharmacokinetics and Pharmacodynamics - Concepts and Applications. 4th ed. 2011.

Gibaldi M, Perrier D. Pharmacokinetics. 2nd ed. revised and expanded. 1982.