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Code for scRNAseq analysis in Pryszlak et al., Cell Reports, 2021

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The DEAD-box helicase DDX56 is a conserved stemness regulator in normal and cancer stem cells

This repository contains custom code used for single cell RNA-sequencing analysis and visualization in Pryszlak M*, Wiggans M*, et al., Cell Reports (2021).

Data Availability

Single cell RNA-sequencing datasets used in this study were obtained from Richards LM et al., Nature Cancer, 2021. Raw sequencing data is available through the European Genome-Phenome Archive (EGAS00001004656; https://www.ebi.ac.uk/ega/studies/) repository. Processed single cell RNA-sequencing data are publically available through the Broad Institute Single-Cell Portal (https://singlecell.broadinstitute.org/single_cell/study/SCP503) and CReSCENT (https://crescent.cloud).

Contact Information

Laura Richards (lauram.richards@mail.utoronto.ca)
Drs. Trevor Pugh (trevor.pugh@utoronto.ca) & Bret Pearson (bret.pearson@sickkids.ca)

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Code for scRNAseq analysis in Pryszlak et al., Cell Reports, 2021

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