This repository contains the implementation of the Physiologically Based Radiopharmacokinetic (PBRPK) Model used in the following paper:
"Physiologically based radiopharmacokinetic (PBRPK) modeling to simulate and analyze radiopharmaceutical therapies: studies of non-linearities, multi-bolus injections, and albumin binding"
Published in EJNMMI Radiopharmacy and Chemistry (2024)
This repository provides a scalable, publicly shared implementation of the PBRPK model in SBML format, along with MATLAB SimBiology scripts for advanced computational simulations.
- MATLAB (with SimBiology toolbox)
If you use this repository, please cite the original paper:
Fele-Paranj, A., Saboury, B., Uribe, C., & Rahmim, A.
Physiologically based radiopharmacokinetic modeling to simulate and analyze radiopharmaceutical therapies: studies of non-linearities, multi-bolus injections, and albumin binding.
EJNMMI Radiopharmacy and Chemistry (2024)
DOI: 10.1186/s41181-023-00236-w