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Post String Method

The post sting method estimates the minimal free energy path on the free energy landscape.

DEMO

Demonstration for the open-closed transition of ribose binding protein.

Features

The replacement of the nth beads.

Requirement (validated version)

  • Python 3.x (3.7.8)
  • matplotlib (3.3.1)
  • pyEMMA (2.5.7)
  • numpy (1.19.1)
  • tqdm (4.48.2)

Installation

Launch string.ipynb and load post-string-input.xvg. post-string-input.xvg should contain three column data (x, y, weight).

Usage

Note

Please cite this paper.

Rikuri Morita, Yasuteru Shigeta, Ryuhei Harada. A post-process to estimate an approximated minimal free energy path based on local centroids. Chem. Phys. Lett. (2021)DOI:[https://doi.org/10.1016/j.cplett.2021.139003]

Author

  • Rikuri Morita*, Yasuteru Shigeta, Ryuhei Harada*.
  • Center for Computational Sciences, University of Tsukuba
  • morita@ccs.tsukuba.ac.jp

License

Post string method is under MIT license.