Skip to content

v1.0

Latest
Compare
Choose a tag to compare
@santiago-es santiago-es released this 05 Sep 00:50
· 6 commits to main since this release
a29585e

Finishing touches on telometer's first draft.

Added:

  • better handling of "gaps" in telomere sequence which are caused by sharp drops in basecalling quality (only relevant when using HAC basecalling). There should now be no discordance between telomere measurements from HAC or SUP basecalled reads as of dorado 0.72
  • batch processing of input bam files so that a maximum of 8GB of memory is needed to run telometer, making it more friendly for running on local machines. This should improve performance when measuring telomeres from high-coverage WGS data.