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Increased QValue cutoff for calibrating PSMs to 0.01 #2392

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merged 6 commits into from
Aug 2, 2024

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Alexander-Sol
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Recent changes to the way Q-Value is calculate have increased Q-Values across the board.

This caused calibration to fail on files that MetaMorpheus used to calibrate successfully.

To address this, I increased the Q-value Notch cut-off for PSMs that are used for calibration from 0.001 to 0.01. I also created a property within CalibrationParameters that reflects this cutoff threshold. Previously it was just a magic number buried in CalibrationTask.

@Alexander-Sol Alexander-Sol changed the title Increased QValue cutoff for calibrating PSMs to 0.005 Increased QValue cutoff for calibrating PSMs to 0.01 Aug 1, 2024
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codecov bot commented Aug 1, 2024

Codecov Report

All modified and coverable lines are covered by tests ✅

Project coverage is 93.69%. Comparing base (f48d118) to head (226b418).

Additional details and impacted files

Impacted file tree graph

@@           Coverage Diff           @@
##           master    #2392   +/-   ##
=======================================
  Coverage   93.69%   93.69%           
=======================================
  Files         139      139           
  Lines       21720    21725    +5     
  Branches     3004     3003    -1     
=======================================
+ Hits        20351    20356    +5     
  Misses        910      910           
  Partials      459      459           
Files Coverage Δ
...TaskLayer/CalibrationTask/CalibrationParameters.cs 100.00% <100.00%> (ø)
...pheus/TaskLayer/CalibrationTask/CalibrationTask.cs 89.73% <100.00%> (+0.13%) ⬆️

@trishorts trishorts merged commit 7fd6aee into smith-chem-wisc:master Aug 2, 2024
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4 participants