PIPET 수련생을 위한 실습교육자료입니다. (R, NCA, Rmarkdown, data science, 임상시험, 약동학/약력학, 논문발표 등)

Validation of Bioequivalence Test Performed by BE R package https://asancpt.github.io/BE-validation

📖 책: R을 사용한 비구획분석과 생물학적동등성 평가, 2020. https://asancpt.github.io/book-ncar

📝 2016, 2017, 2018, 2019 서울아산병원 임상약리학과에 실습 나온 것을 환영합니다. 서브인턴들의 교육을 위해 필요한 자료를 모아두었습니다.

Validation of Noncompartmental Analysis Performed by NonCompart R package https://asancpt.github.io/NonCompart-tests/validation_0.4.4.pdf

Edison App: NONMEM Estimation using R

😄 NonCompart 패키지를 사용해서 2x2 생동성시험의 분산분석 등을 손쉽게 해주는 패키지입니다. https://asancpt.github.io/ncarbe

Reversible Metabolism

Raw R code for manuscript: Hughes JH, Upton RN, Reuter SE, Rozewski DM, Phelps MA, Foster DJR. Development of a physiologically-based pharmacokinetic model for intravenous lenalidomide in mice.

Raw R code used in manuscript: Hughes JH, Phelps MA, Upton RN, et al. Population pharmacokinetics of lenalidomide in patients with B-cell malignancies. Br J Clin Pharmacol. 2019;85(5):924-934.

Empirical MAP Bayes examples and applications. Post-graduate work for Dr. Stephanie Reuter-Lange at University of South Australia.

Raw R code for simulations using South Australia Health Guidelines for vancomycin dosing. Post-graduate work for Dr. Stephanie Reuter-Lange at University of South Australia.

Mixed-Effect Models for In Vitro Xenobiotic Metabolism

Raw R code for manuscript: Hughes JH, Upton RN, Reuter SE, Phelps MA, Foster DJR. Optimising time samples for determining AUC of pharmacokinetic data using non-compartmental analysis.

Models the process of releasing of pharmacological substances.