Multi-omics differential expression and integration analysis in Ferroptosis

Description

In this repository is presented R scripts to reproduce the bioinformatic anaysis in manuscript [LINK when available].

In detail, here is reproduced the necessary steps to perform differential expression analysis of RNA-Seq data using the Bioconductor package DESeq2 and integration analysis of miRNA, gene and proteomics data using WPPI package and miRNA target databases mirTarBase and TargetScan.

Usage

In the Data/ folder you can find output files from the multi-omics integration using WPPI package and miRNA target databases. To access the raw and more details on the datasets, please check the manuscript.

This project was conducted in R software.

Bear in mind, here is only provided an adaptation of the original source code.

Contact

For any inquiries related to this work, please contact me via e-mail ana.galhoz@helmholtz-muenchen.de