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protein-protein-interaction-network

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GitHub Repository associated with the piQTL project (Mapping effects of genome-wide genetic variation to protein-protein interactions reveals molecular mechanisms of complex traits) [ Serohijos & Michnick Lab, Université de Montréal ]

  • Updated Mar 18, 2024
  • Jupyter Notebook

The work focuses on assessing the host-pathogen 21 protein interaction affinity of the coronavirus family, having 44 different variants. In light of these 22 considerations, a GO-semantic scoring function is provided based on Gene Ontology (GO) graphs 23 for determining the binding affinity of any two proteins at the organism level.

  • Updated Feb 17, 2023

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