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The MAPPING_QUALITY_THRESHOLD for GetPileupSummaries is hard coded at 50, but that's not documented anywhere -- and really is only good for BWA aligned reads. There are other mappers that are more spread in their mapping qualities and we lose so many reads.
Instead, please change this tool so that MAPPING_QUALITY_THRESHOLD is a command-line argument (and it's fine to have it set to 50 by default).
Thanks!
The text was updated successfully, but these errors were encountered:
@davidbenjamin Note that this is not exposed in CollectAllelicCounts either and is set to 30 by default. Our default set of read filters is also less stringent. However, we do expose a threshold on minimum base quality. Just a few more things to consider when we unify the two tools!
The MAPPING_QUALITY_THRESHOLD for GetPileupSummaries is hard coded at 50, but that's not documented anywhere -- and really is only good for BWA aligned reads. There are other mappers that are more spread in their mapping qualities and we lose so many reads.
Instead, please change this tool so that MAPPING_QUALITY_THRESHOLD is a command-line argument (and it's fine to have it set to 50 by default).
Thanks!
The text was updated successfully, but these errors were encountered: