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Updated analysis: add PPTID to PB subtyping #590

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jharenza opened this issue Jul 2, 2024 · 0 comments
Open

Updated analysis: add PPTID to PB subtyping #590

jharenza opened this issue Jul 2, 2024 · 0 comments
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@jharenza
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jharenza commented Jul 2, 2024

What analysis module should be updated and why?

PB subtyping

What changes need to be made? Please provide enough detail for another participant to make the update.

Add PPTID subtypes, as they were missed

pb_meta <- histo %>%
filter(pathology_diagnosis %in% path_dx_list_pb$exact_path_dx |
pathology_free_text_diagnosis %in% path_dx_list_pb$path_free_text_exact) %>%
mutate(molecular_subtype_methyl = case_when(
dkfz_v12_methylation_subclass == "PB_FOXR2" ~ "PB, MYC/FOXR2",
dkfz_v12_methylation_subclass == "PIN_RB" ~ "PB, RB1",
dkfz_v12_methylation_subclass == "PB_GRP1A" ~ "PB, Group 1A",
dkfz_v12_methylation_subclass == "PB_GRP1B" ~ "PB, Group 1B",
dkfz_v12_methylation_subclass == "PB_GRP2" ~ "PB, Group 2"))

What input data should be used? Which data were used in the version being updated?

methylation

When do you expect the revised analysis will be completed?

Who will complete the updated analysis?

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