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Add leucine to chymo cleavage motif (#759)
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* correct Within calculation

* update unit tests

* this is the spot

* add space

* update proteasesTsv

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Co-authored-by: MICHAEL SHORTREED <mrshortreed@wisc.edu>
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trishorts and MICHAEL SHORTREED authored Feb 5, 2024
1 parent a9aa0be commit 4269185
Showing 1 changed file with 2 additions and 2 deletions.
4 changes: 2 additions & 2 deletions mzLib/Proteomics/ProteolyticDigestion/proteases.tsv
Original file line number Diff line number Diff line change
@@ -1,8 +1,8 @@
Name Sequences Inducing Cleavage Sequences Preventing Cleavage Cleavage Terminus Cleavage Specificity PSI-MS Accession Number PSI-MS Name Site Regular Expression Cleavage Mass Shifts Notes
Arg-C R| full MS:1001303 Arg-C (?<=R)(?!P)
Asp-N |D full MS:1001304 Asp-N (?=[BD])
chymotrypsin (don't cleave before proline) "F[P]|,W[P]|,Y[P]|" full MS:1001306 Chymotrypsin (?<=[FYWL])(?!P)
chymotrypsin (cleave before proline) "F|,W|,Y|" full MS:1001306 Chymotrypsin (?<=[FYWL])
chymotrypsin (don't cleave before proline) "F[P]|,W[P]|,Y[P]|,L[P]|" full MS:1001306 Chymotrypsin (?<=[FYWL])(?!P)
chymotrypsin (cleave before proline) "F|,W|,Y|,L|" full MS:1001306 Chymotrypsin (?<=[FYWL])
CNBr M| full MS:1001307 CNBr (?<=M) Homoserine lactone on M
elastase "A|,V|,S|,G|,L|,I|" full Elastase (?<=[AVSGLI])
Glu-C E| full
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