SPARK is an efficient method to identify genes with spatial expression pattern. The intended applications are spatially resolved RNA-sequencing from e.g. Spatial Transcriptomics, slide-seq, or in situ gene expression measurements from e.g. seqFISH, MERFISH.
Shiquan Sun*, Jiaqiang Zhu* and Xiang Zhou#. Statistical analysis of spatial expression pattern for spatially resolved transcriptomic studies, 2020, Nature Methods, in press.
Jiaqiang Zhu, Shiquan Sun and Xiang Zhou#. SPARK-X: non-parametric modeling enables scalable and robust detection of spatial expression patterns for large spatial transcriptomic studies, 2021, Genome Biology, in press.
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