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v12 cnv and fusion frequencies #345

Merged
merged 7 commits into from
Apr 28, 2023
Merged

v12 cnv and fusion frequencies #345

merged 7 commits into from
Apr 28, 2023

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zzgeng
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@zzgeng zzgeng commented Mar 23, 2023

Purpose/implementation Section

What scientific question is your analysis addressing?

Update cnv-frequencies and fusion-frequencies modules with v12 data and change the output column for somatic_mutation to pediatric_cancer

What was your approach?

Change datatypeId column value for the output table from somatic_mutation to pediatric_cancer

What GitHub issue does your pull request address?

d3b-center/ticket-tracker-OPC#527
d3b-center/ticket-tracker-OPC#528

Directions for reviewers. Tell potential reviewers what kind of feedback you are soliciting.

Which areas should receive a particularly close look?

Is there anything that you want to discuss further?

Is the analysis in a mature enough form that the resulting figure(s) and/or table(s) are ready for review?

Yes

Results

What types of results are included (e.g., table, figure)?

What is your summary of the results?

Reproducibility Checklist

  • The dependencies required to run the code in this pull request have been added to the project Dockerfile.
  • This analysis has been added to continuous integration.

Documentation Checklist

  • This analysis module has a README and it is up to date.
  • This analysis is recorded in the table in analyses/README.md and the entry is up to date.
  • The analytical code is documented and contains comments.

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@kelseykeith kelseykeith left a comment

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Overall this looks great!

  • Except for the PMTL column in the cnv-frequencies table (see Issues below), the structure of the new v12 tables for both modules match the v11 version.
  • The data mostly match except for adjustments made with the new release.
  • The fusion-frequencies module has been updated to use the DGD fusions in the data/ directory, not the file inside the module
  • The datatypeId column was correctly updated in both modules.

Minor Issues:

  • @ewafula, the PMTL annotation is being removed in v12 correct? So it's right that it's missing from the cnv-frequencies table when it was present in v11.
  • I suggested removing the .gitignore in the fusion-frequencies module since the files are all under 10Mb, well under GitHub's file size limit of 100Mb, but if we're moving away from this model it can be left alone

analyses/fusion-frequencies/results/.gitignore Outdated Show resolved Hide resolved
@ewafula
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ewafula commented Mar 25, 2023

Overall this looks great!

  • Except for the PMTL column in the cnv-frequencies table (see Issues below), the structure of the new v12 tables for both modules match the v11 version.
  • The data mostly match except for adjustments made with the new release.
  • The fusion-frequencies module has been updated to use the DGD fusions in the data/ directory, not the file inside the module
  • The datatypeId column was correctly updated in both modules.

Minor Issues:

  • @ewafula, the PMTL annotation is being removed in v12 correct? So it's right that it's missing from the cnv-frequencies table when it was present in v11.
  • I suggested removing the .gitignore in the fusion-frequencies module since the files are all under 10Mb, well under GitHub's file size limit of 100Mb, but if we're moving away from this model it can be left alone

@kelseykeith, that is correct PMTL is no longer in all MTP tables. All MTP were all updated to exclude PMTL in a previous PR.

@ewafula ewafula changed the title V12 cnv freq v12 cnv and fusion freq Mar 25, 2023
@ewafula ewafula changed the title v12 cnv and fusion freq v12 cnv and fusion frequencies Mar 25, 2023
@kelseykeith
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Thanks for the changes @zzgeng! This looks good now, approved

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3 participants